A Study on the Critical Mechanism of Nifedipine-Induced Gingival Overgrowth in Spontaneously Hypertensive Rats.
نویسندگان
چکیده
منابع مشابه
Therapy for nifedipine-induced gingival overgrowth by saireito in rats
OBJECTIVE A calcium antagonist, nifedipine, causes gingival overgrowth as a side effect. It has been confirmed that the Japanese traditional medicine, Saireito, inhibits the nifedipine-induced proliferation of gingival fibroblasts in vitro. We performed an in vivo experiment to determine whether Saireito has a therapeutic use in the treatment of nifedipine-induced gingival overgrowth. METHODS...
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15 صفحه اولNonsurgical Management of Nifedipine Induced Gingival Overgrowth
Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less when compared to the effects of phenytoin and cyclosp...
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Age dependency of cyclosporin A-induced gingival overgrowth in rats.
Effects of age on cyclosporin A- (CsA) induced gingival overgrowth were investigated in Fischer rats. Rats 15, 30, 45, and 60 days old were fed a diet containing cyclosporin A (120-200 micrograms/g) for 40 days. Gingival overgrowth was estimated by measuring the gingival sulcus depth with a thin color slide probe under a stereoscopic dissecting microscope. The youngest group (15 days old) of ra...
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ژورنال
عنوان ژورنال: Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)
سال: 2003
ISSN: 0385-0110,1880-408X
DOI: 10.2329/perio.45.289